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Source, antibacterial activity, and routes of administration are described on p. 274. Albeit mostly well tolerated, this drug may cause several adverse effects including hepatic damage, hypersensitivity with flu-like symptoms, disconcerting but harmless red/orange discoloration of body fluids, and enzyme induction (failure of oral contraceptives).
Pain stimuli are detected by physiological receptors (sensors, nociceptors) least differentiated morphologically, viz. , free nerve endings. The body of the bipolar afferent first-order neuron lies in a dorsal root ganglion. Nociceptive impulses are conducted via unmyelinated (C-fibers, conduction velocity 0. 2–2. 0 m/s) and myelinated axons (A?-fibers, 5–30 m/s).

 

The disruption and incoherence of ideation is symbolically represented at the top left (A) and the normal psychic state is illustrated as on p. 237 (bottom left). Neuroleptics After administration of a neuroleptic, there is at first only psychomotor dampening. Tormenting paranoid ideas and hallucinations lose their subjective importance; however, the psychotic processes still persist.
Hyperlipoproteinemias can be caused genetically (primary h. ) or can occur in obesity and metabolic disorders (secondary h). Elevated LDL-cholesterol serum concentrations are associated with an increased risk of atherosclerosis, especially when there is a concomitant decline in HDL concentration (increase in LDL:HDL quotient).

 

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